SKI3011 syllabus
Evidence Synthesis 2: Statistics in Systematic Reviewing
- Period 5 · 2.5 ECTS · skills training
- Coordinator and tutor: Prof. dr. Maurice Zeegers
- Prerequisite: Evidence Synthesis 1 (SKI3010); an argued exception is possible. Recommended: Research Methods II (SKI1005), Presentation Skills (SKI2007), and an idea of the research field you are most interested in.
This module
In SKI3011 you choose your own research topic and carry out a systematic review and meta-analysis from start to finish. You write a protocol and register it on protocols.io, manage screening and data extraction in Covidence, and learn to run meta-analyses in R: effect sizes for binary and continuous outcomes, proportions and correlations, forest plots, heterogeneity, publication bias, subgroup analysis and meta-regression. The pace is higher than in SKI3010, and you get more freedom.
The first six weeks are carbon-based. You write your own R code, and each week a short paper quiz checks whether you can read and interpret the code and output from the previous lecture. In week 7 the module turns silicon-based with a demonstration of Claude Code. From then on you may also let AI do part of the work in your own project, but you do not have to. You finish with a draft paper (introduction, methods, results) plus R code and dataset, which you complete in PRO3017.
Learning outcomes
After this module you can:
- formulate a review question and register a review protocol;
- manage screening and data extraction in Covidence;
- read, write and interpret R code for meta-analysis of binary, continuous, proportion and correlation data;
- assess heterogeneity and publication bias, and explore heterogeneity with subgroup analysis and meta-regression;
- write a draft systematic review with reproducible R code and dataset;
- give constructive feedback on a review and its code written by others;
- explain how an AI tool such as Claude Code can support a meta-analysis, and check its output.
Assessment
| Component | Weight | Notes |
|---|---|---|
| Quizzes 1-5 (paper, in the tutorial, interpreting R code and output) | 25% | Best 4 of 5 count |
| A4 Individual peer review | 15% | Individual |
| A5 Final paper + R code + dataset | 60% | Group of 1-3 students |
| A1-A3 Progress assignments | 0% | Pass/fail |
The final paper and the peer review are graded with the rubrics.
Rules
- Groups. You work in a group of 1 to 3 students on a topic of your own choice. Every member is responsible for the whole paper and code. The peer review is individual.
- Quizzes. Paper quiz at the start of the tutorial, no devices. The best 4 of 5 quizzes count. A missed quiz scores 0 and has no separate resit. With documented illness you can take the quiz in the next tutorial.
- Deadlines. Hand in via the submission form. Always include your R script and your dataset (csv), so that your results can be reproduced.
- AI is allowed as a tutor from week 1 and as a co-worker from week 7; see AI use. Every paper contains a short AI-use paragraph in the methods.
- Announcements are sent through Canvas and reach you by e-mail.