SKI3010 syllabus
Evidence Synthesis 1: Study Designs in Systematic Reviewing
- Period 4 · 2.5 ECTS · skills training
- Coordinator and tutor: Prof. dr. Maurice Zeegers
- Prerequisite: Statistics I (SSC2061); an argued exception is possible. Recommended: Research Methods I (SKI1004), Research Methods II (SKI1005), Presentation Skills (SKI2007).
- Textbook: Bouter, Zeegers and Li, Textbook of Epidemiology, 2nd edition (Wiley), available via the library (KeyLinks).
This module
SKI3010 lays the foundation. You learn the basic concepts of epidemiology and statistics that every systematic review relies on: study designs, measures of frequency and association, bias and risk of bias, and the logic of meta-analysis. You apply them right away. All groups work on the same review question: does exposure to thimerosal-containing vaccines increase the risk of autism spectrum disorder in children? Starting from the primary studies, you extract study characteristics, assess risk of bias with the Newcastle-Ottawa Scale, extract quantitative data, perform a meta-analysis first by hand and then in JASP, and write a paper that follows PRISMA 2020. At the end you give individual written feedback on the paper of another group.
Learning outcomes
After this module you can:
- explain the basic concepts of systematic reviews, observational study designs and measures of frequency and association;
- extract study characteristics and assess the risk of bias of observational studies with the Newcastle-Ottawa Scale;
- extract quantitative data and prepare it for meta-analysis;
- perform and interpret a meta-analysis by hand and in JASP;
- write a systematic review that follows PRISMA 2020;
- give constructive feedback on a systematic review written by others.
Assessment
| Component | Weight | Notes |
|---|---|---|
| Quizzes 1-4 (paper, in the tutorial) | 20% | Best 3 of 4 count |
| A5 Individual peer review | 15% | Individual |
| A6 Final paper | 65% | Group of 1-3 students |
| A1-A4 Progress assignments | 0% | Pass/fail |
The final paper and the peer review are graded with the rubrics.
Rules
- Groups. You work in a group of 1 to 3 students and stay in that group for the whole module. Every member is responsible for the whole paper. The peer review is individual.
- Quizzes. Paper quiz at the start of the tutorial, no devices. The best 3 of 4 quizzes count. A missed quiz scores 0 and has no separate resit. With documented illness you can take the quiz in the next tutorial.
- Deadlines. Hand in via the submission form. The progress assignments A1 to A4 are pass/fail; you get feedback in the next tutorial.
- Lectures are optional. Tutorials are where you start your assignment with help from the tutor.
- AI is allowed as a tutor; see AI use. Every paper contains a short AI-use paragraph in the methods.
- Announcements are sent through Canvas and reach you by e-mail.